News

May 1st 2013: Mouse Strains Newly Available from the MMRRC

Dear Researchers,

The Mutant Mouse Regional Resource Centers (MMRRC) distributes and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines with potential value for the genetics and biomedical research community. The MMRRC is a single repository with a national network of four breeding and distribution facilities coordinated by an information and service center. The MMRRC is supported by the National Institutes of Health.

Now available for Distribution: 4 mouse models are newly available from the MMRRC repository. Strain Detail Sheets for each of these strains can be accessed through the stock numbers below.

Click here to view these newly available strains in the MMRRC catalog

The Repository’s newest additions: 17 strains have recently been accepted and will be available through the MMRRC. If you register interest, we will notify you when the strain is available; you will then have the opportunity to place an order. The average wait time for a newly accepted strain to become available for distribution is seven months from time MMRRC receives it from the donor.
To register interest, find the MMRRC product in the catalog listing, then click on the star icon in the left hand column.

Click here to view these newly accepted strains in the MMRRC catalog

Donate your Strain: The mouse models you have created are a valuable resource. Please consider submitting your strain to make it available for distribution to the scientific community.
We strongly encourage donating modified MMRRC strains and/or mice made from MMRRC ES cells. Providing a published paper, in-press manuscript, or access to your phenotype data, will guarantee acceptance and archiving of your strain with the MMRRC.

service@mmrrc.org

sacoord@mmrrc.org

www.mmrrc.org

Newly available strains from April 2013

Cryo-archive

MMRRC:036257-JAX,FVB/N-Ehmt1^{Tg(Tyr)2265COve}/Mmjax

MMRRC:036265-JAX,FVB/N-In(10C1;Ccdc53)4Ove/Mmjax

MMRRC:036804-MU,FVB/N-Tg(CAG-Diap3)771Lesp/Mmmh
Research applications include: Cell Biology, Sensorineural, Models for Human Disease

Newly accepted strains from April 2013

Accepted

MMRRC:036888-JAX,B6;129S6-Rr23^tm1Axvi/Mmjax
Research applications include: Research Tools, Models for Human Disease, Developmental Biology

MMRRC:036894-JAX,B6;129S6-Rr24^tm1Axvi/Mmjax
Research applications include: Developmental Biology, Research Tools, Models for Human Disease

MMRRC:036895-JAX,B6;129S6-Rr25^tm1Axvi/Mmjax
Research applications include: Developmental Biology, Research Tools, Models for Human Disease

MMRRC:036897-MU,FVB/N-Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/Mmmh
Research applications include: Cancer, Developmental Biology, Research Tools, Cell Biology, Models for Human Disease

MMRRC:036898-UNC,129S-Omp^tm1Flm/Mmnc
Research applications include: Sensorineural, Neurobiology

MMRRC:036899-UNC,129S-Bex1^{Gt(OST125186)Lex}/Mmnc
Research applications include: Cancer, Sensorineural, Models for Human Disease, Research Tools, Cell Biology, Neurobiology

MMRRC:036900-JAX,FVB;129S6-Astl^tm1Dean/Mmjax
Research applications include: Reproduction, Developmental Biology, Research Tools, Cell Biology

MMRRC:036901-UNC,B6.Cg-Tg(Il2-emGFP,Il21-mCherry)1Wjl/Mmnc
Research applications include: Immunology and Inflammation

MMRRC:036902-UNC,B6.Cg-Tg(Il2-emGFP,Il21-mCherry)6Wjl/Mmnc
Research applications include: Immunology and Inflammation

MMRRC:036903-UNC,B6.Cg-Tg(Il21-mCherry)1Wjl/Mmnc
Research applications include: Immunology and Inflammation

MMRRC:036904-UCD,B6.FVB(Cg)-Tg(Esr2-EGFP)ID169Gsat/Mmucd
Research applications include: Cell Biology, Neurobiology, Endocrine Deficiency, Research Tools, Cardiovascular, Models for Human Disease, Developmental Biology, Cancer, Reproduction, Immunology and Inflammation

MMRRC:036905-UCD,B6.FVB(Cg)-Tg(Agtr1a-EGFP)NZ44Gsat/Mmucd
Research applications include: Models for Human Disease, Endocrine Deficiency, Reproduction, Cell Biology, Metabolism, Diabetes, Cardiovascular, Neurobiology, Immunology and Inflammation, Research Tools, Developmental Biology

MMRRC:036906-MU,B6.FVB-Tg(tetO-Ccnd1*T286A,-luc)11233Kuw/Mmmh
Research applications include: Research Tools, Cell Biology, Models for Human Disease, Cancer, Developmental Biology

MMRRC:036907-UCD,B6.FVB(Cg)-Tg(Avp-EGFP)HF200Gsat/Mmucd
Research applications include: Research Tools, Internal/Organ, Reproduction, Cardiovascular, Neurobiology

MMRRC:036908-UCD,C57BL/6-Tg(APOE-SCARB1)8Arem/Mmucd
Research applications include: Models for Human Disease, Cardiovascular

MMRRC:036915-UCD,B6.FVB(Cg)-Tg(Gpr26-cre)KO250Gsat/Mmucd
Research applications include: Cell Biology, Neurobiology, Developmental Biology, Research Tools

MMRRC:036916-UCD,B6.FVB(Cg)-Tg(Drd1a-cre)FK150Gsat/Mmucd
Research applications include: Neurobiology

Donate your Strain: The mouse models you have created are a valuable resource. Please consider submitting your strain to make it available for distribution to the scientific community

We strongly encourage donating modified MMRRC strains and/or mice made from MMRRC ES cells. Providing a published paper, in-press manuscript, or access to your phenotype data, will guarantee acceptance and archiving of your strain with the MMRRC.

Terms and Benefits of submitting to the MMRRC.

Please direct questions to MMRRC Customer Service at: service@mmrrc.org

Phone: 800.910.2291 (North America) or 1.530.757.5710 (International).

Apr 16th 2013: Recruitment for Assistant Director: Operations

The UC Davis Mouse Biology Program (MBP) is seeking an interested and experienced individual as its Assistant Director: Operations.  The MBP is an academic teaching, research, service center and shared resource at UC Davis established to develop, study, and conduct education and training in genetic manipulation of the laboratory mouse.  The MBP consists of an interdisciplinary group of scientists, staff, and students from across the UC Davis campus organized under the administrative oversight of the Center for Comparative Medicine.  The mission of the MBP is to develop, disseminate, and deliver mutant mouse technologies in the post-genomic era through the application of mouse genetics and biology in biomedical research. The MBP provides centralized and coordinated expertise in mouse biology “from concept through creation” by offering state-of-the-art laboratories, facilities, and services in an enriched environment for students, trainees, and investigators utilizing genetically-altered mice in research. Please visit the MBP career page for more details: http://www.mousebiology.org/career.php

Apr 16th 2013: Mouse Production and Phenotyping Discussion Group

The Mouse Biology Program at the University of California, Davis is please to extend invitations to the Knock Out Mouse Project:  Production and Phenotyping Discussion Group luncheon, to be held Monday, April 22, at Experimental Biology 2013.  This free lunch workshop will feature speakers from the DTCC (Davis, Toronto, Charles River and CHORI) consortium, and is hosted by Charles River Laboratories.  Seating is limited!  Click on the link below for further information and to make your reservations.

Mouse Production and Phenotyping Discussion Group

When
Monday, April 22, 2013 11:30 AM  -  1:00 PM

Where
The Westin Waterfront Hotel
425 Summer Street
Commonwealth Ballroom C
Boston, Massachusetts 02210 

View Event Summary

RSVP
Tuesday, April 16, 2013

Apr 1st 2013: Mouse Strains Newly Available from the MMRRC

Dear Researchers,

The Mutant Mouse Regional Resource Centers (MMRRC) distributes and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines with potential value for the genetics and biomedical research community. The MMRRC is a single repository with a national network of four breeding and distribution facilities coordinated by an information and service center. The MMRRC is supported by the National Institutes of Health.

Get `em while they last:
The following Live colonies will soon be taken off the shelf. Once off the shelf, these strains will only be available as cryopreserved germplasm or mice from cryo recovery.


Order the following strains distributed from the MMRRC by placing the order online by the dates indicated below to receive mice from the Live colonies.

Order by April 30th, 2013

• MMRRC:036116-JAX, B6.Cg-Mapt^tm1Hnd Tg(MAPT)1Gds/Mmjax
• MMRRC:036227-JAX, FVB/N-Narfl^{Tg(Tyr)2379G-3bOve}/Mmjax
• MMRRC:036230-JAX, FVB/N-Dhx29^{TgTn(sb-cHS4,Tyr)2354AOve}/Mmjax
• MMRRC:036268-JAX, FVB/N-Ubap2l^{TgTn(sb-cHS4,Tyr)2326F-3b2Ove}/Mmjax
• MMRRC:036303-JAX, STOCK Mir188^tm1Mtm/Mmjax

Now available for Distribution: 2 mouse models are newly available from the MMRRC repository. Strain Detail Sheets for each of these strains can be accessed through the stock numbers below.

Click here to view these newly available strains in the MMRRC catalog

The Repository’s newest additions: 14 strains have recently been accepted and will be available through the MMRRC. If you register interest, we will notify you when the strain is available; you will then have the opportunity to place an order. The average wait time for a newly accepted strain to become available for distribution is seven months from time MMRRC receives it from the donor.
To register interest, find the MMRRC product in the catalog listing, then click on the star icon in the left hand column.

Click here to view these newly accepted strains in the MMRRC catalog

Donate your Strain: The mouse models you have created are a valuable resource. Please consider submitting your strain to make it available for distribution to the scientific community.
We strongly encourage donating modified MMRRC strains and/or mice made from MMRRC ES cells. Providing a published paper, in-press manuscript, or access to your phenotype data, will guarantee acceptance and archiving of your strain with the MMRRC.

service@mmrrc.org

sacoord@mmrrc.org

www.mmrrc.org

Newly available strains from March 2013

Cryo-archive

MMRRC:036561-UNC,129S6(B6)-Pgk^t2tm1Dao/Mmnc
Research applications include: Cell Biology, Metabolism, Reproduction, Developmental Biology, Models for Human Disease

MMRRC:036780-UNC,129S-Ryr1^{Gt(L3625D)Gmei}/Mmnc
Research applications include: Research Tools

Newly accepted strains from March 2013

Accepted

MMRRC:036806-JAX,FVB.Cg-Atp2a2^tm1Ges/Mmjax
Research applications include: Cancer, Models for Human Disease, Cell Biology, Apoptosis, Diabetes, Cardiovascular, Dermatology

MMRRC:036807-JAX,FVB.Cg-Atp2b4^tm1Ges/Mmjax
Research applications include: Cell Biology, Reproduction, Cardiovascular, Immunology and Inflammation, Apoptosis

MMRRC:036808-JAX,B6.Cg-Atp2c1^tm1Ges/Mmjax
Research applications include: Cell Biology, Models for Human Disease, Cancer, Dermatology, Apoptosis

MMRRC:036809-MU,MaD1/Mmmh
Research applications include: Neurobiology

MMRRC:036810-UCD,SW.FVB/N-Tg(GNB1L,TBX1,GP1BB,SEPT5)23Rak/Mmucd
Research applications include: Sensorineural, Developmental Biology, Models for Human Disease, Cardiovascular, Immunology and Inflammation

MMRRC:036811-UCD,FVB.Cg-Tbx1^tm1Rak/Mmucd
Research applications include: Models for Human Disease, Developmental Biology, Sensorineural, Cardiovascular

MMRRC:036812-MU,B6.Cg-Cacna1a ^rkr/Mmmh
Research applications include: Models for Human Disease, Neurobiology

MMRRC:036813-MU,C57BL/6J-Nlrp3^m5Btlr/Mmmh
Research applications include: Research Tools, Models for Human Disease, Cell Biology, Virology, Immunology and Inflammation

MMRRC:036814-UNC,CD1;B6-Kdm6a^{tm1a(EUCOMM)Wtsi}/Mmnc
Research applications include: Developmental Biology, Reproduction

MMRRC:036815-UNC,B6;129S-Soat2^tm1.2Llr/Mmnc
Research applications include: Metabolism, Cardiovascular, Models for Human Disease

MMRRC:036818-UNC,B6.129-Stxbp3a^tm1Jepn/Mmnc
Research applications include: Metabolism, Diabetes, Obesity

MMRRC:036819-UNC,B6.129-Stx4a^tm1Jepn/Mmnc
Research applications include: Metabolism, Diabetes, Obesity

MMRRC:036820-UNC,B6.Cg-Tg(CMV-tTA,tetO-Stxbp3a)2Jepn/Mmnc
Research applications include: Metabolism, Diabetes, Obesity

MMRRC:036896-MU,B6.129-Piwil1^tm1Hfl/Mmmh

Donate your Strain: The mouse models you have created are a valuable resource. Please consider submitting your strain to make it available for distribution to the scientific community

We strongly encourage donating modified MMRRC strains and/or mice made from MMRRC ES cells. Providing a published paper, in-press manuscript, or access to your phenotype data, will guarantee acceptance and archiving of your strain with the MMRRC.

Terms and Benefits of submitting to the MMRRC.

Please direct questions to MMRRC Customer Service at: service@mmrrc.org

Phone: 800.910.2291 (North America) or 1.530.757.5710 (International).

Mar 23rd 2013: Frank Ruddle, genetics pioneer, dies at 83

March 22, 2013, 9:21 am – Francis “Frank” Ruddle, Yale professor and inventor of the transgenic mouse, died this month at age 83. One former colleague called him a “serial visionary” for his pioneering work in genetics. A Sterling Professor of Biology, Ruddle “helped lay the … View Full Article
Source: Google News