News
May 12th 2012: Groundbreaking New Course in Mouse Pathobiology
May 03 2012 – The Center for Genomic Pathology and UC Davis Extension announce a new course in the online series Pathobiology of the Mouse: Mouse as a Model for Mammary Cancer. This groundbreaking course is the first in the second tier of the program and is designed for experienced investigators at the doctoral level working in mammary tumor biology. The course includes case studies and interactive conferences with expert faculty. Now open for enrollment, the course is scheduled to launch on June 11, 2012 Press Release
Mar 26th 2012: Mouse Strains Newly Available from the MMRRC
Mouse Strains Newly Available from the MMRRC
Get ‘em while they last: The following Live colonies will soon be taken off the shelf. Once off the shelf, these strains will only be available as cryopreserved germplasm or mice from cryo recovery. Place your orders online by the dates below to receive mice from the Live colonies.
Order the following 3 strains distributed from the MMRRC at UNC, Chapel Hill by Friday, March 30
Order the following 2 strains distributed from the MMRRC at UC Davis by Monday, April 30
Now available for Distribution: 32 mouse models are newly available from the MMRRC repository. Strain Detail Sheets for each of these strains can be accessed through the stock numbers below.
Click here to view these newly available strains in the MMRRC catalog
The Repository’s newest additions: 28 strains have recently been accepted and will be available through the MMRRC. If you register interest, we will notify you when the strain is available; you will then have the opportunity to place an order. The average wait time for a newly accepted strain to become available for distribution is seven months from time MMRRC receives it from the donor.
To register interest, find the MMRRC product in the catalog listing, then click on the 
in the left hand column.
Click here to view these newly accepted strains in the MMRRC catalog
Donate your Strain: The mouse models you have created are a valuable resource. Please consider submitting your strain to make it available for distribution to the scientific community.
We strongly encourage donating modified MMRRC strains and/or mice made from MMRRC ES cells. Providing a published paper, in-press manuscript, or access to your phenotype data, will guarantee acceptance and archiving of your strain with the MMRRC.
service@mmrrc.org
sacoord@mmrrc.org
www.mmrrc.org
Newly available strains from February 2012
Breeder pairs
MMRRC:036211-JAX, B6.Cg-Mapttm1Hnd Tg(MAPT*V337M)1Gds/Mmjax
Research applications include: Models for Human Disease, Neurobiology
MMRRC:036512-UCD, C57BL/6N-Tg(CAG-Flpo)1Afst/Mmucd
Research applications include: Models for Human Disease
Cryo-archive
MMRRC:030045-UNC, FVB.BKa-Ptprcb
Research applications include: Cancer, Immunology and Inflammation, Developmental Biology, Research Tools, Hematology, Cell Biology, Models for Human Disease, Diabetes/Obesity
MMRRC:032809-UCD, STOCK Tg(Dlg3-cre)KG118Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
MMRRC:034249-UCD, B6;129P2-Scaf8Gt(XA153)Byg/Mmucd
Research applications include: Cardiovascular, Research Tools, Models for Human Disease, Reproduction, Developmental Biology, Neurobiology
MMRRC:034356-UCD, B6;129P2-Scaf4Gt(XC749)Byg/Mmucd
Research applications include: Cardiovascular, Models for Human Disease, Developmental Biology, Research Tools, Metabolism, Cell Biology, Neurobiology, Internal/Organ
MMRRC:034375-UCD, B6NCr.129P2-Akap13Gt(AG0213)Wtsi/Mmucd
Research applications include: Cell Biology, Reproduction, Endocrine Deficiency, Cardiovascular, Models for Human Disease, Developmental Biology, Cancer, Immunology and Inflammation
MMRRC:034376-UCD, B6NCr;129P2-Akap13Gt(CSJ306)Byg/Mmucd
Research applications include: Cell Biology, Endocrine Deficiency, Cardiovascular, Models for Human Disease, Reproduction, Developmental Biology, Cancer, Immunology and Inflammation
MMRRC:034377-UCD, B6NCr.129P2-Akap13Gt(CSJ288)Byg/Mmucd
Research applications include: Models for Human Disease, Developmental Biology, Cancer, Immunology and Inflammation, Cell Biology, Endocrine Deficiency, Cardiovascular
MMRRC:034666-UCD, B6;129P2-Gtf2iGt(XE029)Byg/Mmucd
Research applications include: Developmental Biology, Neurobiology, Cardiovascular, Research Tools, Models for Human Disease, Reproduction
MMRRC:034758-UCD, B6;129P2-Dock4Gt(CSH308)Byg/Mmucd
Research applications include: Neurobiology, Developmental Biology, Models for Human Disease, Cardiovascular, Research Tools, Diabetes/Obesity
MMRRC:034791-UCD, B6;129P2-1110012J17RikGt(RRQ026)Byg/Mmucd
Research applications include: Developmental Biology, Research Tools, Cardiovascular, Models for Human Disease
MMRRC:036050-UNC, B6.129S1-Mrgprdtm5Mjz/Mmnc
Research applications include: Neurobiology
MMRRC:036118-UNC, B6.129S1-Mrgprdtm1.1(cre)And/Mmnc
Research applications include: Neurobiology
MMRRC:036164-UCD, STOCK Tg(Bsx-cre)NS106Gsat/Mmucd
Research applications include: Neurobiology, Developmental Biology, Research Tools, Cell Biology
MMRRC:036166-UCD, STOCK Tg(Grm2-cre)MR89Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
MMRRC:036168-UCD, STOCK Tg(Nr5a1-cre)SB4Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
MMRRC:036169-UCD, STOCK Tg(Ptger2-cre)SC30Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036170-UNC, B6.129S4 -Ash2lGt(S3-11A1)Sor/Mmnc
Research applications include: Research Tools, Developmental Biology
MMRRC:036181-UCD, STOCK Tg(Nbl1-EGFP)NY104Gsat/Mmucd
Research applications include: Cell Biology, Neurobiology, Developmental Biology, Research Tools
MMRRC:036186-UCD, STOCK Tg(Vmn1r206-EGFP)PI35Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036188-UCD, STOCK Tg(Ppp1r17-cre)NL163Gsat/Mmucd
Research applications include: Cell Biology, Neurobiology, Developmental Biology, Research Tools
MMRRC:036189-UCD, STOCK Tg(Neurod4-cre)OU98Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036194-UCD, B6.129X1-Ptpn11tm3Bgn/Mmucd
Research applications include: Cancer, Internal/Organ, Developmental Biology, Immunology and Inflammation, Cardiovascular, Models for Human Disease, Hematology
MMRRC:036203-UCD, STOCK Tg(Chrnb4-cre)OL57Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036207-UCD, STOCK Tg(Nts-cre)RH4Gsat/Mmucd
Research applications include: Neurobiology, Developmental Biology, Research Tools, Cell Biology
MMRRC:036319-UCD, STOCK Tg(Trnp1-EGFP)PU26Gsat/Mmucd
Research applications include: Neurobiology, Developmental Biology, Research Tools, Cell Biology
MMRRC:036467-UCD, STOCK Tg(Peg10-EGFP)OD131Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
MMRRC:036468-UCD, STOCK Tg(Pcp2-tdTomato)PK9Gsat/Mmucd
Research applications include: Neurobiology, Developmental Biology, Research Tools, Cell Biology
MMRRC:036472-UCD, STOCK Tg(Pde1b-cre)OZ114Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
ES cell line
MMRRC:036284-JAX, B6;129-Mycntm1Psk Myctm2Fwa cDKO2 mES cells
Research applications include: Cell Biology
MMRRC:036285-JAX, B6;129-Mycntm1Psk Myctm2Fwa cDKO3 mES cells
Research applications include: Cell Biology
Newly accepted strains from February 2012
Accepted
MMRRC:036497-MU, FVB/N-Tg(Zp3*)1Dean/Mmmh
Research applications include: Reproduction, Developmental Biology, Cell Biology
MMRRC:036498-MU, B6;129P2-Slc39a4tm2Gka/Mmmh
Research applications include: Metabolism, Cancer, Research Tools, Developmental Biology, Apoptosis, Models for Human Disease, Cell Biology
MMRRC:036506-UCD, STOCK Tg(Ckm-GCGR)1Qwg/Mmucd
Research applications include: Diabetes/Obesity, Models for Human Disease, Metabolism, Research Tools
MMRRC:036508-UCD, B6.Cg-Tg(CD68-Tnfrsf13c)MB21Nemz/Mmucd
Research applications include: Immunology and Inflammation, Developmental Biology
MMRRC:036510-UCD, B6.Cg-IghaThy1aGpi1a/J-Tg(UBC-scFv)68Nemz/Mmucd
Research applications include: Research Tools, Immunology and Inflammation, Apoptosis
MMRRC:036511-UCD, B6.Cg-IghaThy1aGpi1a/J-Tg(UBC-scFv)16Nemz/Mmucd
Research applications include: Immunology and Inflammation, Apoptosis, Research Tools
MMRRC:036515-UNC, STOCK Tg(Ednrb-icre)1Lby/Mmnc
Research applications include: Cell Biology, Research Tools, Internal/Organ, Neurobiology, Developmental Biology, Models for Human Disease
MMRRC:036521-UCD, B6N;129S6-Raf1tm1.1Bgn/Mmucd
Research applications include: Models for Human Disease, Developmental Biology
MMRRC:036522-JAX, FVB/N-Spink5Tn(Pgk2-sb10,sb-Tyr)1498OveMmjax
Research applications include: Models for Human Disease, Developmental Biology, Dermatology
MMRRC:036523-JAX, FVB/N-Invsinv/Mmjax
Research applications include: Developmental Biology, Models for Human Disease, Cardiovascular, Internal/Organ
MMRRC:036527-UCD, STOCK Tg(Plagl1-EGFP)MH26Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036528-UCD, STOCK Tg(Gprin3-tdTomato)TL3Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
MMRRC:036529-UCD, STOCK Tg(Npy2r-tdTomato)Pl39Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036530-UCD, STOCK Tg(Olig2-tdTomato)TH39Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
MMRRC:036531-UCD, STOCK Tg(Prox1-tdTomato)TA76Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036532-UCD, STOCK Tg(Chrna5-cre)SN83Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
MMRRC:036533-UCD, STOCK Tg(Cnr1-cre)RY75Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036534-UCD, STOCK Tg(Slc32a1-cre)RO29Gsat/Mmucd
Research applications include: Research Tools, Cell Biology, Neurobiology, Developmental Biology
MMRRC:036535-UCD, STOCK Tg(Rgs14-cre)SR63Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036539-UCD, STOCK Tg(Dlx1-tdTomato)TB85Gsat/Mmucd
Research applications include: Developmental Biology, Cell Biology, Research Tools, Neurobiology
MMRRC:036540-UCD, STOCK Tg(Fezf2-tdTomato)SZ89Gsat/Mmucd
Research applications include: Cell Biology, Neurobiology, Developmental Biology, Research Tools
MMRRC:036541-UCD, STOCK Tg(Hspa12b-tdTomato)TH25Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036542-UCD, STOCK Tg(Syt6-tdTomato)TK14Gsat/Mmucd
Research applications include: Cell Biology, Neurobiology, Developmental Biology, Research Tools
MMRRC:036543-UCD, STOCK Tg(Galr3-cre)SU30Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036544-UCD, STOCK Tg(Opn4-cre)SA9Gsat/Mmucd
Research applications include: Cell Biology, Neurobiology, Developmental Biology, Research Tools
MMRRC:036545-UCD, STOCK Tg(Oxtr-cre)ON66Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036546-UCD, STOCK Tg(Sepw1-cre)NP72Gsat/Mmucd
Research applications include: Cell Biology, Neurobiology, Developmental Biology, Research Tools
MMRRC:036547-UCD, STOCK Tg(Tlx3-cre)PL56Gsat/Mmucd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
Jan 9th 2012: New MMRRC Strains.
Dear Researchers,
The Mutant Mouse Regional Resource Centers (MMRRC) distributes and cryopreserves scientifically valuable, genetically engineered mouse strains and mouse ES cell lines with potential value for the genetics and biomedical research community. The MMRRC is a single repository with a national network of four breeding and distribution facilities coordinated by an information and service center. The MMRRC is supported by the National Institutes of Health
Get ‘em while they last: The following Live colonies will be taken off the shelf this month. Once off the shelf, this strain will only be available as cryopreserved germplasm or mice from cryo recovery. Place your orders online by Tuesday, January 31 to receive mice from the Live colony.
The Repository’s newest additions: The following mouse models strains have recently been accepted and will be available through the MMRRC. If you register interest, we will notify you when the strain is available; you will then have the opportunity to place an order. The average wait time for a newly accepted strain to become available for distribution is seven months from time MMRRC receives it from the donor.
To register interest, select the MMRRC stock number below, then click the star in the first column of the catalog.
View the newly accepted strains in the MMRRC catalog
MMRRC:036401-JAX, C3Fe;B6-Tbc1d14L5Jcs5/Mmjax
Research applications include: Developmental Biology
MMRRC:036402-UCD, C57BL/6J-Pik3ap1m1Btlr/Mmcd
Research applications include: Immunology and Inflammation
MMRRC:036457-JAX, B6.129S4-Sagtm1Jnc Tg(Sag*3A240)2Seva/Mmjax
Research applications include: Sensorineural
MMRRC:036458-JAX, B6.129S4-Sagtm1Jnc Tg(Sag*3A50)1Seva/Mmjax
Research applications include: Sensorineural
MMRRC:036459-MU, B6.129S4-Sagtm1Jnc Tg(Sag*Tr12)2Seva/Mmmh
Research applications include: Sensorineural
MMRRC:036460-MU, B6.129S4-Sagtm1Jnc Tg(Sag*Tr4)1Seva/Mmmh
Research applications include: Sensorineural
MMRRC:036461-MU, B6.129S4-Sagtm1Jnc Tg(Sag)1Seva/Mmmh
Research applications include: Sensorineural
MMRRC:036462-UNC, B6.129S6-Pdx1tm1.2(CFP)Mgn/Mmnc
Research applications include: Internal/Organ, Diabetes/Obesity, Research Tools
MMRRC:036463-UNC, STOCK-Sox17tm1.3(Cre.GFP)Mgn/Mmnc
Research applications include: Internal/Organ, Diabetes/Obesity, Research Tools
MMRRC:036464-UCD, 129S-Hfe2tm2Nca/Mmcd
Research applications include: Neurobiology, Developmental Biology, Models for Human Disease, Cardiovascular, Research Tools, Hematology
MMRRC:036465-UCD, STOCK Tg(Lgals1-EGFP)OA32Gsat/Mmcd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036466-UCD, STOCK Tg(Nrp2-EGFP)SH25Gsat/Mmcd
Research applications include: Neurobiology, Developmental Biology, Research Tools, Cell Biology
MMRRC:036467-UCD, STOCK Tg(Peg10-EGFP)OD131Gsat/Mmcd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036468-UCD, STOCK Tg(Pcp2-TOM)PK9Gsat/Mmcd
Research applications include: Neurobiology, Developmental Biology, Research Tools, Cell Biology
MMRRC:036469-UCD, STOCK Tg(Chrnb3-cre)SM93Gsat/Mmcd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036470-UCD, STOCK Tg(Ebf2-cre)NP183Gsat/Mmcd
Research applications include: Neurobiology, Developmental Biology, Research Tools, Cell Biology
MMRRC:036471-UCD, STOCK Tg(Nr5a1-cre)SB15Gsat/Mmcd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036472-UCD, STOCK Tg(Pde1b-cre)OZ114Gsat/Mmcd
Research applications include: Neurobiology, Developmental Biology, Research Tools, Cell Biology
MMRRC:036473-UCD, STOCK Tg(Shf-cre)SO5Gsat/Mmcd
Research applications include: Developmental Biology, Research Tools, Cell Biology, Neurobiology
MMRRC:036474-UNC, B6.129P2-Kdm3atm1.1Yzha/Mmnc
Research applications include: Reproduction, Cardiovascular, Diabetes/Obesity, Developmental Biology
MMRRC:036475-UCD, 129S6.Cg-Tg(Krt14-TFRC)#Lmil/Mmcd
Research applications include: Internal/Organ, Dermatology, Models for Human Disease, Immunology and Inflammation, Cell Biology, Metabolism, Hematology, Cancer, Research Tools
Donate your Strain: The mouse models you have created are a valuable resource. Please consider submitting your strain to make it available for distribution to the scientific community
We strongly encourage donating modified MMRRC strains and/or mice made from MMRRC ES cells. Providing a published paper, in-press manuscript, or access to your phenotype data, will guarantee acceptance and archiving of your strain with the MMRRC.
Terms and Benefits of submitting to the MMRRC.
Please direct questions to MMRRC Customer Service at: service@mmrrc.org
Phone: 800.910.2291 (North America) or +1.530.757.5710 (International).
Sep 29th 2011: $34 million grant awarded to create mouse models of human diseases
A consortium of U.S. and Canadian health science partners, including the University of California, Davis, has been awarded $34 million in grants by the National Institutes of Health to support creation of mouse models of such human diseases as cancer, obesity, diabetes and heart disease.
The new five-year cooperative agreement funds the second phase of the Knockout Mouse Project — or KOMP — first funded by the NIH in 2006. Knockout mice are genetically customized mice that have individual genes turned off or “knocked out,” or have a gene ramped up, to make them either more prone or more resistant to specific diseases.
“In this consortium, we have assembled world experts in mouse stem cell biology, genetics, breeding, and phenotypic analysis who are dedicated to ensuring the successful outcome of KOMP2, on time and on budget,” said Kent Lloyd, director of the UC Davis Mouse Biology Program and principal investigator and director of the newly funded project. Lloyd is also a professor of anatomy, physiology and cell biology at the UC Davis School of Veterinary Medicine, and serves as the school’s associate dean for research.
Click here to read more
Sep 20th 2011: Education App from NHGRI
NHGRI has developed its first education ‘App’!
If you use an iPhone, iPad, or iPod Touch, you can now have free access to the popular NHGRI Talking Glossary of Genetics anywhere you go.
In addition to offering easy-to-understand written definitions, users can listen to an NHGRI scientist explain each term and provide contextual learning tips. The glossary App contains nearly 200 color illustrations and more than thirty 3-D animations that illustrate genetic concepts. The mobile version of the glossary includes all of the bells and whistles of the online version, including new and simplified search methods, easy-to-find terms of interest, alphabetical navigation to search functions, and lists of related terms.
There’s even a “Test Your Gene Knowledge” quiz, so users can check their understanding of the glossary’s contents.
The majority of the glossary terms are studied in middle school, high school, and collegiate science classes. Teachers at all levels were used to help compile the terms and evaluate the glossary during development.
It’s free and it’s fun. Either go to the iTunes App Store and search “talking glossary” or click on the App Store link below.
http://itunes.apple.com/us/app/talking-glossary-of-genetics/id428340581?mt=8&ls=1
